A clinical phenotype refers to the observable characteristics or traits of an individual that result from the interaction of their genetic makeup with environmental factors. In research, clinical phenotyping involves identifying and describing these traits in order to better understand disease mechanisms, diagnosis, prognosis, and treatment outcomes. This may involve analyzing various clinical features such as symptoms, physical characteristics, laboratory test results, and imaging findings to classify and categorize individuals into subgroups based on their phenotypic characteristics. Clinical phenotyping plays a crucial role in personalized medicine and precision healthcare by helping to tailor treatments to individual patients based on their unique clinical profiles.